The City Market area, the Battery, and Rainbow Row are popular places to visit if you haven’t been to Charleston before. Downtown is always a moving target as to what’s fun and fresh. There’s a beautiful neighborhood around The Citadel called Hampton Park Terrace. There is a big park with huge palm trees and bike paths, and you’ll find plenty of local restaurants.
I love Park Circle as a great up-and-coming destination, too. It has a lot of trendy restaurants and is full of breweries and distilleries that are doing very well. Johns Island is another area that’s expanding. Along Maybank Road you’ll find wonderful independent eateries and development.